A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
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Updated
Oct 5, 2026
A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
Simulate the C. Elegans worm brain in your browser and interact with the worm as it moves around
A fruit fly connectome as a drone pilot. Camera -> fly eyes -> spiking brain -> descending neurons -> drone. Live 3D demo in your browser.
Experimental Drosophila-inspired camera-to-robot bridge. Working mock neural backend, optical flow, IMU feedback and UDP motor control. MaleCNS integration planned.
A 302 neuron network on the real C. elegans wiring diagram, with a steering layer for local language models.
Graph theory analysis of brain MRI data
Python library for analysis of neuroanatomical data.
micapipe from the Multimodal imaging and connectome analysis lab (http://mica-mni.github.io) at the Montreal Neurological Institute. Read The Docs documentation below
STAGIN: Spatio-Temporal Attention Graph Isomorphism Network
A dynamic connectome mapping module in python.
A performant, powerful query framework to search for network motifs
Real fly anatomy and model-output starter. Custom license requires web UI and repository attribution.
Connectome Mapper 3 is a BIDS App that implements full anatomical, diffusion, resting/state functional MRI, and recently EEG processing pipelines, from raw T1 / DWI / BOLD , and preprocessed EEG data to multi-resolution brain parcellation with corresponding connection matrices.
Embodied Drosophila: 138,639-neuron whole-brain connectome simulation (FlyWire v783) in a biomechanical body (NeuroMechFly v2 / MuJoCo). Vision, olfaction, gustation, flight, and emergent behaviors — all from the real connectome.
Compose chunk operators to create a pipeline for local or distributed petabyte-scale computation
A unified framework for skeletonization, morphological analysis, and connectivity analysis.
Emergent behaviour and neural dynamics in artificial agents tracking odour plumes
A prediction-based extension of network-based statistics.
Please use the new version of LiFE: www.github.com/brain-life/encode
A Hugo theme with backlinks for online communities
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